Particle size measurement of lipoprotein fractions using diffusion-ordered NMR spectroscopy
Abstract The sizes of certain types of lipoprotein particles have been associated with an increased risk of cardiovascular disease. However, there is currently no gold standard technique for the determination of this parameter. Here, we propose an analytical procedure to measure lipoprotein particles sizes using diffusion-ordered nuclear magnetic resonance spectroscopy (DOSY). The method was tested […]
Surface fitting of 2D diffusion-edited 1H NMR spectroscopy data for the characterisation of human plasma lipoproteins
Abstract Determining the concentration and size of lipoprotein complexes is very important due to their role in cardiovascular diseases and metabolic disorders. However, standard methods for lipoprotein fractionation are manual and time consuming and cannot be used as standard diagnostic tools. Because different subclasses of lipoproteins have different radii and, hence, different diffusion velocities, we […]
From LAB to market
Last year we published 19 scientific articles in international journals. We are a metabolomics company halfway between research and clinical practice, a scientific research group in a business environment that is committed to translational research. We carry out scientific collaborations with research groups from universities, research institutions, hospitals and companies in the biomedical sector both […]
Biosfer was awarded with the INNOWWIDE: a high competitive European call
Recently our CEO, Núria Amigó, was invited to participate in the first INNOWWIDE Focus Group, a virtual meeting organized by Steinbeis 2i innovative + international, as an INNOWWIDE funding recipient representative, to evaluate the call impact and to get insight the entire process, enabling to see those activities which we were good at and those […]
GlycA as a new biomarker in rheumatoid arthritis
The research group in Immunology at the University of Oviedo with the participation of Dr. Javier Rodríguez-Carrio has published a study in which one of the variables from our glycoprotein test has been identified as an emerging biomarker for stratification and decision-making in early-stage rheumatoid arthritis. If you want to know more about this publication, […]
Advanced lipoprotein profile disturbances in type 1 diabetes mellitus: a focus on LDL particles
Our lipoprotein profile, Liposcale (CE), in Cardiovascular Diabetology: “Advanced lipoprotein profile disturbances in type 1 diabetes mellitus: a focus on LDL particles” The research groups of Sant Pau and Hospital Clinic lead by Dr. Didac Mauricio, Dr. Emilio Ortega and Dr. Antonio Amor have published a relevant study including more than 500 type 1 Diabetic […]
El nostre test Liposcale a la pràctica clínica
Estem molt contents d’anunciar que la Societat Espanyola d’Arteriosclerosi ha redactat un consens sobre l’ús clínic de ressonància magnètica nuclear per a l’estudi de les lipoproteïnes utilitzant el nostre test Liposcale®. El test Liposcale® caracteritza perfils de lipoproteïna plasmàtica i detecta alteracions que predisposen a malalties cardiovasculars, permetent una acció clínica preventiva més enllà dels […]
Our Liposcale test in clinical practice
We are very happy to announce that the Spanish Arteriosclerosis Society has drawn up a consensus on the clinical use of Nuclear Magnetic Resonance for the study of lipoproteins using our Liposcale® test. The Liposcale® test is an advanced lipoprotein analysis which detects the alterations that predispose to cardiovascular disease. Liposcale test allows a preventive […]
We are virtually at the European Arteriosclerosis Society congress
This week the 88th edition of the Congress of the European Arteriosclerosis Society was held in virtual format. The congress has included a large number of basic and clinical research presentations by members of the scientific community. Our research team has participated with the presentation of two Science at a Glance and a poster in […]
Glycoprotein Profile Assessed by 1H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study.
Abstract Plasma glycoproteins are a composite biomarker of inflammation and can be detected by 1H-NMR. The aim of this study was to prospectively appraise the clinical value of plasma glycoproteins assessed by 1H-NMR in people living with HIV (PLWH). A total of 221 patients with HIV infection were recruited and studied at baseline and at 48 […]
