Science and methodology

Science begins before measurement

We define what information the study needs, how the samples should be collected and stored, and what controls and analyses are required to answer the scientific question.

Researcher processing a sample next to a visualisation of analytical data
From question to plan

A coherent design connects every decision in the project

The question, the design, the samples and the analytical strategy are agreed from the outset. These decisions determine what can be concluded at the end of the study.

  1. Question and objective

    We clarify what the project needs to answer and whether the approach is exploratory, confirmatory or longitudinal.

  2. Design and feasibility

    We review groups, time points, matrices, available volume and pre-analytical conditions before committing to the analysis.

  3. Analytical strategy

    We define a global, targeted or combined approach according to the question, the sample and the evidence required.

  4. Analysis and interpretation

    Statistical plan, longitudinal and multivariate models, validation and reports with tables and figures, according to the design and objective of the study.

Rigour and traceability

Documented rigour from sample to result

We document samples, measurements and data processing with procedures and controls defined for each project.

Pre-analytical

Samples

We define the matrix, volume, collection, storage, transport and acceptance criteria before starting.

Laboratory

Analytical control

Quality controls in every batch and criteria adapted to the technique and the intended use of the data.

Data

Traceable processing

We record transformations, exclusion criteria and analysis workflows so that the result is reproducible.

Interpretation

Supported conclusions

We relate each conclusion to the design, the results obtained and the limits of the available evidence.

Quality management system certified to ISO 9001 and ISO 13485.

Trust and governance

The project is also designed around the data

Before starting, we agree with each team how samples, data and results will be managed.

01

Scope and responsibilities

We define what is received, what is analysed, who is involved and what is delivered.

02

Access and confidentiality

We organise access and the communication of results according to the roles and agreements in place.

The exact arrangements depend on the type of study, the agreements, the consents and the applicable legal or regulatory requirements.

Two researchers examining a sample and an illustrative NMR spectrum
The next step

Let’s move your next project forward

Tell us what you are working on and we will explore the most suitable approach with you.

Talk to us about your project