Research & Clinical Trials

By scientists, for scientists

We combine ¹H-NMR metabolomics, biomarker analysis, biostatistics and sample coordination to answer biomedical questions in studies and clinical trials.

Two research professionals preparing samples in the laboratory
Scientific services

The approach is built around the question

  1. Metabolomics

    Quantitative ¹H-NMR metabolic profiling and targeted analysis of specific pathways, to characterise the metabolic phenotype and generate hypotheses.

    What your team receives
    • Metabolic phenotype: patterns and pathways
    • Global or targeted analytical design
    • Concentrations, statistical analysis and report
    • Global metabolic profile
    • Targeted quantification

  2. Biomarker analysis

    ELISA, immunoturbidimetry, biochemistry and ultracentrifugation to measure the markers the study requires, with controls defined for each project.

    What your team receives
    • Evaluation of hypotheses and biomarker candidates
    • Specific, traceable measurements
    • Results that can be combined with metabolomics and clinical data
    • ELISA and immunoassays
    • Immunoturbidimetry
    • Ultracentrifugation
    • Molecular biology

  3. Bioinformatics and data analysis

    Statistics, bioinformatics and models on data generated by Biosfer or provided by your team, with quality control and combined omics and clinical data.

    What your team receives
    • Patterns, biomarkers and predictive models
    • Reproducible analysis and multi-omics integration
    • Visualisations, reports or digital environments
    • Quality control
    • Statistical analysis
    • Multi-omics integration
    • Models and tools

  4. Biosfer Trials · clinical research and CRO

    Study coordination, sample operations, data management and biostatistics within a single scientific team.

    What your team receives
    • One scientific contact for the whole study
    • Traceable samples and data across sites
    • Analysis, report and publication support
    • Study start-up
    • Site coordination
    • Central laboratory
    • Biostatistics
How we can help

The studies we support and how we start

Research questions

  1. Which biological processes are altered in my cohort or model?
  2. Can we identify and validate diagnostic, prognostic or response biomarkers?
  3. Why do some participants respond to the treatment or intervention and others do not?
  4. Are there distinct profiles or subgroups within the same cohort?
  5. How do we connect molecular data with clinical and lifestyle variables?
  6. What can we learn from the data and samples we already have?

Research areas

  • Metabolism and nutrition
  • Cardiometabolic health
  • Performance and muscle function
  • Microbiota and host interaction
  • Inflammation and immunity
  • Ageing and cellular function

Who we work with

Research groups and universities
Academic, preclinical and translational projects: from broad exploration to the validation of candidates.
Hospitals and translational units
Cohorts, clinical variables and questions close to clinical practice.
Clinical trial sponsors
Coordination, samples, data and biostatistics within the agreed scope, in single-centre or multicentre studies.
Biotech and life sciences
Validation, biomarkers and knowledge applicable to the development of products and services.

How we start

  1. Step 1 We start from your question and study design

    Hypothesis, cohort or intervention, available matrix and the decision the result must support.

  2. Step 2 We define the scope and the combination of services

    Metabolomics, biomarkers, data analysis or study coordination, according to what each phase of the project needs.

  3. Step 3 You receive data, interpretation and follow-up

    Traceable results, a report with the interpretation and a scientific contact throughout the study.

Why Biosfer for research

A track record in biomedical research

Since 2013 we have measured samples, analysed data and coordinated projects with research groups, hospitals and companies.

Biomedical and translational experience

A spin-off of Universitat Rovira i Virgili and IRB CatSud, with scientific publications of our own and with partners.

Analytical and bioinformatics services

We bring measurement, data analysis and interpretation together in a single scientific workflow.

Consortium coordination

We take part in and coordinate national and international public–private consortia.

From analysis to publication

We take part in interpreting the results and writing the manuscripts, with analyses and figures prepared for scientific journals.

Collaboration models

We step in where the project needs us

From a specific analytical service to a broader scientific collaboration, we adapt to what each study requires.

Analytical service

Measurements, data and deliverables defined for a specific phase of the study.

Scientific collaboration

Analytical strategy, analysis, interpretation and manuscript writing, with the agreed level of involvement.

Consortia and funded projects

Scientific and technical participation in competitive proposals and collaborative initiatives.

Your next project

Request a proposal for your study

Tell us what you want to investigate and we will propose an approach tailored to your study.

Request a proposal