Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes.
Scientific reports ·2016 ·37 citations
Núria Amigó, Roger Mallol, Mercedes Heras, Sergio Martínez-Hervás, Francisco Blanco Vaca, Joan Carles Escolà-Gil, Núria Plana, Óscar Yanes, Lluís Masana, Xavier Correig
- Publication type
- Original article
- Citations
- 37 (OpenAlex, 16 October 2026)
- PMID
- 26778677
Field of study
- Type 2 diabetes
Analytical platform
- NMR lipoprotein profiling
Matrix
- Serum or plasma
Related
Biomarkers
Publications on the same biomarkers
- Liposcale: a novel advanced lipoprotein test based on 2D diffusion-ordered 1H NMR spectroscopy. 2015 · Journal of lipid research · 198 citations
- HDL Triglycerides: A New Marker of Metabolic and Cardiovascular Risk. 2019 · International journal of molecular sciences · 107 citations
- An in-depth analysis shows a hidden atherogenic lipoprotein profile in non-diabetic chronic kidney disease patients. 2019 · Expert opinion on therapeutic targets · 53 citations
Show 16 more Show less
- Relationship between noninvasive scores of nonalcoholic fatty liver disease and nuclear magnetic resonance lipoprotein abnormalities: A focus on atherogenic dyslipidemia. 2017 · Journal of clinical lipidology · 45 citations
- Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure. 2021 · Scientific reports · 35 citations
- Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia. 2022 · Circulation · 25 citations
- Remarkable quantitative and qualitative differences in HDL after niacin or fenofibrate therapy in type 2 diabetic patients. 2015 · Atherosclerosis · 23 citations
- Improvement of the omega 3 index of healthy subjects does not alter the effects of dietary saturated fats or n-6PUFA on LDL profiles. 2017 · Metabolism: clinical and experimental · 19 citations
- Patients With Systemic Lupus Erythematosus Show an Increased Arterial Stiffness That is Predicted by IgM Anti-β2 -Glycoprotein I and Small Dense High-Density Lipoprotein Particles. 2019 · Arthritis care & research · 18 citations
- Effect of diets rich in either saturated fat or n-6 polyunsaturated fatty acids and supplemented with long-chain n-3 polyunsaturated fatty acids on plasma lipoprotein profiles. 2017 · European journal of clinical nutrition · 18 citations
- Lipid Profile Rather Than the LCAT Mutation Explains Renal Disease in Familial LCAT Deficiency. 2019 · Journal of clinical medicine · 17 citations
- Triglycerides as Determinants of Global Lipoprotein Derangement: Implications for Cardiovascular Prevention. 2025 · International journal of molecular sciences · 9 citations
- Advanced lipoprotein parameters could better explain atheromatosis in non-diabetic chronic kidney disease patients. 2021 · Clinical kidney journal · 8 citations
- Gelsolin: a new biomarker of disease activity in SLE patients associated with HDL-c. 2020 · Rheumatology (Oxford, England) · 8 citations
- Increasing the complexity of lipoprotein characterization for cardiovascular risk in type 2 diabetes. 2024 · European journal of clinical investigation · 7 citations
- Metabolomics Approach to Identify Biomarkers of Acute and Subacute Mastitis in Milk Samples: A Pilot Case-Control Study. 2024 · Metabolites · 4 citations
- Chronic kidney disease induces a distinct lipidomic signature and accelerates atherosclerosis progression in a novel minipig model. 2026 · Laboratory animal research · 1 citation
- Assessment of physical status and analysis of lipidomic and metabolomic alterations in patients with Post-COVID-19 condition. 2026 · PloS one · 1 citation
- Cardiovascular risk and metabolomic profile in adolescents: A comparative study between anorexia nervosa, normal weight, and obesity. 2026 · Clinica e investigacion en arteriosclerosis