Low-Grade Inflammation and Glycoproteins: New Evidence After Metabolic Surgery
Low-Grade Inflammation: The Invisible Thread Connecting Obesity and Cardiometabolic Risk Obesity is not merely an excess of weight; it is a complex disease associated with a chronic, low-grade inflammatory state—silent yet persistent—that contributes to the development of type 2 diabetes, hypertension, fatty liver, and cardiovascular disease. This state arises from the expansion of adipose tissue, […]
Obesity Affects Men and Women Differently: New Insights into the Lipoprotein Profile
A recent study published in Lipids in Health and Disease (Santisteban et al., 2025) offers a new perspective on how sex and body mass index influence lipoprotein metabolism, even in individuals considered metabolically healthy. The research, authored by Victoria Santisteban(1,2), Anallely López-Yerena (1,3,4), Natàlia Muñoz-Garcia (1), Gemma Vilahur (1,5), Lina Badimon (1,5,6), and Teresa Padró […]
Gut microbiota and metabolism associated with CAR-T therapy response in multiple myeloma
Gut microbiota and metabolism associated with CAR-T therapy response in multiple myeloma A recent work published by Mireia Uribe-Herranz¹⁺², Aina Oliver-Caldés¹⁺³, Neus Martínez-Micaelo⁴, Marta Español-Rego², Maria Val-Casals¹⁺⁵, Roberto Martínez-Soler¹, Elisa Rubio-Garcia⁶⁺⁷⁺⁸⁺⁹, Valeria Brunello¹, Erik Z. Mihelic¹, Nela Klein-González¹⁺²⁺⁵, Daniel Benítez-Ribas², Núria Amigó⁴⁺¹⁰⁺¹¹, Andrea Vergara⁶⁺⁷⁺⁹⁺¹², Valentin Ortiz-Maldonado³, Luis Gerardo Rodríguez-Lobato¹⁺³, Julio Delgado³, Iñaki Ortiz […]
Triglycerides: More Than a Marker — A Driver of Cardiovascular Risk
Triglycerides: More Than a Marker — A Driver of Cardiovascular Risk Introduction: The Residual Risk Beyond LDL Cholesterol For decades, LDL cholesterol has been considered the main enemy in cardiovascular prevention. However, numerous studies — including the FOURIER-OLE trial — have shown that even patients with extremely low LDL-C levels continue to experience […]
ASCAHIFA and Biosfer Teslab on Familial Hypercholesterolemia Day
ASCAHIFA and Biosfer Teslab join forces to advance the diagnosis of familial hypercholesterolemia with Liposcale® On September 24, we celebrate Familial Hypercholesterolemia (FH) Day, a hereditary genetic condition that causes very high levels of LDL cholesterol from birth and greatly increases the risk of developing premature cardiovascular disease. It is estimated that FH affects 1 […]
When LDL Cholesterol Doesn’t Tell the Whole Story: A Clinical Case of Hidden Cardiovascular Risk
The Challenge of Residual Risk in Cardiovascular Health Cardiovascular diseases remain the leading cause of death worldwide.Despite preventive efforts—such as controlling LDL cholesterol, blood pressure, and glucose levels—many individuals still suffer heart attacks or strokes even with apparently “normal” values. This phenomenon is known as residual cardiovascular risk, and it accounts for up […]
NMR Metabolomics in Animal Models: A Key Tool for Translational Research
In biomedical research, animal models represent a fundamental tool for understanding the pathophysiological mechanisms of human diseases and for exploring new therapeutic strategies. They allow for the controlled reproduction of complex clinical conditions, the study of disease progression—particularly in chronic or metabolic disorders—and the evaluation of interventions before their application in humans. In […]
Liposcale and Glycoscale in Cardiovascular Risk Prediction in Type 2 Diabetes
Each year, cardiovascular diseases (CVD) are responsible for more than 4 million deaths in Europe, making them the leading cause of mortality on the continent. These diseases include heart attacks, strokes, and other conditions related to the circulatory system. For decades, the prevention and treatment of CVD have focused on lowering LDL cholesterol (commonly known as “bad […]
Beyond LDL: A Comprehensive Approach to Cardiovascular Health
Each year, cardiovascular diseases (CVD) are responsible for more than 4 million deaths in Europe, making them the leading cause of mortality on the continent. These diseases include heart attacks, strokes, and other conditions related to the circulatory system. For decades, the prevention and treatment of CVD have focused on lowering LDL cholesterol (commonly known as “bad […]
Ketone bodies and their potential as biomarkers in relapsed/refractory diffuse large B-cell lymphoma
New Findings in DLBCL Research Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. While most patients respond favorably to initial treatment, a significant percentage develop relapsed or refractory (R/R) disease, which limits therapeutic options and worsens prognosis. A recent study published in the journal Cancers has identified two […]
