Publications and Conferences

Publications

Malo, Ana Irene et al. Glycoprotein Profile Assessed by 1H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study. J. Clin. Med. 9, no. 5: 1344. (2020).

Amigó, Nuria, et al. Habitual Fish Consumption, n‐3 Fatty Acids, and Nuclear Magnetic Resonance Lipoprotein Subfractions in Women. Journal of the American Heart Association 9.5 (2020)

Fuertes-Martín, Rocío, et al. Human Serum/Plasma Glycoprotein Analysis by 1H-NMR, an Emerging Method of Inflammatory Assessment. Journal of Clinical Medicine 9.2 (2020).

Fernández‐Cidón, Bárbara, et al. Precipitated sdLDL: An easy method to estimate LDL particle size. Journal of Clinical Laboratory Analysis (2020).

Rodríguez-Borjabad, Cèlia, et al. Efficacy of therapeutic lifestyle changes on lipid profiles assessed by NMR in children with familial and non-familial hypercholesterolemia. Clínica e Investigación en Arteriosclerosis (English Edition) 32.2 (2020): 49-58.

Insenser M, et al. 2D diffusion-ordered 1H-NMR spectroscopy lipidomic profiling after oral single macronutrient loads: Influence of obesity, sex, and female androgen excess. Molecular Nutrition & Food Research, May, 2020.

Llauradó, G et al. Specific Nuclear Magnetic Resonance Lipoprotein Subclass Profiles and Central Arterial Stiffness in Type 1 Diabetes Mellitus: A Case Control Study. J. Clin. Med. 2019, 8, 1875.

Lamiquiz-Moneo, I.; Civeira, F.; Gómez-Coronado, D.; Blanco-Vaca, F.; Villafuerte-Ledesma, H.M.; Gil, M.; Amigó, N.; Mateo-Gallego, R.; Cenarro, A. Lipid Profile Rather Than the LCAT Mutation Explains Renal Disease in Familial LCAT Deficiency. J. Clin. Med. 2019, 8, 1860

R Fuertes-Martin et al. Glycoprotein A and B height to weight ratios as obesity-independent novel biomarkers of low-grade chronic inflammation in women with polycystic ovary syndrome (PCOS). Journal of proteome research, 2019.

Gil M et al, Lipid Profiling Using 1H NMR Spectroscopy. In: Methods in Molecular Biology. 2019

Parra et al. Patients With Systemic Lupus Erythematosus Show an Increased Arterial Stiffness That is Predicted by IgM. Arthritis care & research 71 (1), 116-125, 2019

Girona J., et al. HDL Triglycerides: A New Marker of Metabolic and Cardiovascular Risk.  International Journal of Molecular Sciences 20 (13), 3151, 2019

Parra S. et al. Gelsolin: a new biomarker of disease activity in SLE patients associated with HDL-C. Rheumatology (2019)

Rodríguez-Tomàs et al. Serum Paraoxonase-1-Related Variables and Lipoprotein Profile in Patients with Lung or Head and Neck Cancer: Effect of Radiotherapy. Antioxidants 8 (7), 213, 2019.

Miranda J et al., “Metabolic profiling and targeted lipidomics reveals a disturbed lipid profile in mothers and fetuses with intrauterine growth restriction” Scientific Reports, Vol 11, 8(1): 13614, Sep 2018

Malagelada C et al., “Metabolomic signature of the postpandrial experience”. Neurogastroenterol Motil., vol 13:e13447, Aug 2018.

Parra S et al. “SLE patients show an increased arterial stiffness that is predicted by IgM-anti-ß2-glycoprotein I and small dense HDL particles”. Arthritis Care Res (Hoboken), May 2018.

Pichler G et al, “LDL particle size and composition and incident cardiovascular disease in a South-European population: The Hortega-Liposcale Follow-up Study. Int J Cardiol, vol 1, 264:172-178. Mar 2018.

Rodríguez-Borjabad C et al, “Lipoprotein profile assessed by 2D-1H-NMR and subclinical artherosclerosis in children with familial hypercholesterolaemia”. Atherosclerosis, Vol 270:177-122. Jan 2018

Barrilero R et al, LipSpin: A New Bioinformatics Tool for Quantitative 1H NMR Lipid Profiling. Anal Chem. 2018

Rodriguez-Garcia, E. et al. Implications of the Mediterranean diet and physical exercise on the lipid profile of metabolically healthy obese women as measured by nuclear magnetic resonance spectroscopy (1H NMR). Chemistry and Physics of Lipids (2018).

R. Barrilero et al., “Unravelling and Quantifying the ‘NMR-Invisible’ Metabolites Interacting with Human Serum Albumin by Binding Competition and T2 Relaxation-Based Decomposition Analysis,” J. Proteome Res., vol. 16, no. 5, pp. 1847–1856, May 2017.

C. B. Dias et al., “Effect of diets rich in either saturated fat or n-6 polyunsaturated fatty acids and supplemented with long-chain n-3 polyunsaturated fatty acids on plasma lipoprotein profiles,” Eur. J. Clin. Nutr., May 2017.

C. B. Dias et al., “Improvement of the omega 3 index of healthy subjects does not alter the effects of dietary saturated fats or n-6PUFA on LDL profiles,” Metabolism, vol. 68, pp. 11–19, Mar. 2017.

A. J. Amor et al., “Relationship between noninvasive scores of nonalcoholic fatty liver disease and nuclear magnetic resonance lipoprotein abnormalities: A focus on atherogenic dyslipidemia,” J. Clin. Lipidol., vol. 11, no. 2, p. 551–561.e7, Mar. 2017.

J. Girona et al., “Circulating PCSK9 levels and CETP plasma activity are independently associated in patients with metabolic diseases,” Cardiovasc. Diabetol., vol. 15, no. 1, p. 107, Dec. 2016.

A. J. Amor et al., “Nuclear magnetic resonance lipoprotein abnormalities in newly-diagnosed type 2 diabetes and their association with preclinical carotid atherosclerosis,” Atherosclerosis, vol. 247, pp. 161–169, Apr. 2016.

D. Ibarretxe et al., “Impact of epidermal fatty acid binding protein on 2D-NMR–assessed atherogenic dyslipidemia and related disorders,” J. Clin. Lipidol., vol. 10, no. 2, p. 330–338.e2, Mar. 2016.

D. Ibarretxe et al., “Circulating PCSK9 in patients with type 2 diabetes and related metabolic disorders,” Clinica e Investig. en Arterioscler., vol. 28, no. 2, pp. 71–78, Mar. 2016.

N. Amigó et al., “Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes.,” Sci. Rep., vol. 6, p. 19249, Jan. 2016.

L. Brugnara et al., “Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.,” PLoS One, vol. 10, no. 8, p. e0136348, 2015.

R. Barrilero et al., “Design and evaluation of standard lipid prediction models based on 1H-NMR spectroscopy of human serum/plasma samples,” Metabolomics, vol. 11, no. 5, pp. 1394–1404, Oct. 2015.

S. Samino et al., “Metabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess,” Sci. Rep., vol. 5, no. 1, p. 11496, Sep. 2015.

T. Padro et al., “Lipidomic changes of LDL in overweight and moderately hypercholesterolemic subjects taking phytosterol- and omega-3-supplemented milk,” J. Lipid Res., vol. 56, no. 5, pp. 1043–1056, May 2015.

P. Hernández-Alonso et al., “Effect of pistachio consumption on plasma lipoprotein subclasses in pre-diabetic subjects,” Nutr. Metab. Cardiovasc. Dis., vol. 25, no. 4, pp. 396–402, Apr. 2015.

R. Mallol et al., “Liposcale: a novel advanced lipoprotein test based on 2D diffusion-ordered 1H NMR spectroscopy.,” J. Lipid Res., vol. 56, no. 3, pp. 737–46, Mar. 2015.

L. Masana et al., “Remarkable quantitative and qualitative differences in HDL after niacin or fenofibrate therapy in type 2 diabetic patients,” Atherosclerosis, vol. 238, no. 2, pp. 213–219, Feb. 2015.

J. Gomez et al., “Dolphin: a tool for automatic targeted metabolite profiling using 1D and 2D 1H-NMR data,” Anal. Bioanal. Chem., vol. 406, no. 30, pp. 7967–7976, Dec. 2014.

P. Hernández-Alonso et al., “Beneficial Effect of Pistachio Consumption on Glucose Metabolism, Insulin Resistance, Inflammation, and Related Metabolic Risk Markers: A Randomized Clinical Trial,” Diabetes Care, vol. 37, no. 11, pp. 3098–3105, Nov. 2014.

Ú. Catalán et al., “Biomarkers of food intake and metabolite differences between plasma and red blood cell matrices; a human metabolomic profile approach,” Mol. Biosyst., vol. 9, no. 6, p. 1411, Jun. 2013.

R. Mallol et al., “Human serum/plasma lipoprotein analysis by NMR: Application to the study of diabetic dyslipidemia,” Prog. Nucl. Magn. Reson. Spectrosc., vol. 70, pp. 1–24, Apr. 2013.

N. Cañellas et al., “Use of multivariate chemometric algorithms on 1H NMR data to assess a soluble fiber (Plantago ovata husk) nutritional intervention,” Chemom. Intell. Lab. Syst., vol. 121, pp. 1–8, Feb. 2013.

R. Mallol et al., “Particle size measurement of lipoprotein fractions using diffusion-ordered NMR spectroscopy,” Anal. Bioanal. Chem., vol. 402, no. 7, pp. 2407–2415, Mar. 2012.

R. Mallol et al., “Surface fitting of 2D diffusion-edited 1H NMR spectroscopy data for the characterisation of human plasma lipoproteins,” Metabolomics, vol. 7, no. 4, pp. 572–582, Dec. 2011.

M. Vinaixa et al., “Metabolomics Reveals Reduction of Metabolic Oxidation in Women with Polycystic Ovary Syndrome after Pioglitazone-Flutamide-Metformin Polytherapy,” PLoS One, vol. 6, no. 12, p. e29052, Dec. 2011.

Conferences

Gil M. et al. Lipid Profiling Of Lipoprotein Fractions Using 1H-Nmr Spectroscopy. Atherosclerosis 287, e220, 2019.

Amigó N Exploring liporpotein patterns in general population with advanced 1H-NMR testing. Madrid, 25-26 November, Cardiologist 2018

M Bermudez. El análisis de subfracciones lipídicas y PCSK9 evidencia un perfil aterogénico oculto en la enfermedad renal crónica”.  Oral Presentation. 16-19 Novembre, Madrid XLVIII Congreso nacional de la S.E.N y IX Congreso iberoamericano de nefrología

Amigó “Anàlisi del perfil lipoproteic (Liposcale) i perfil inflamatori del plasma” XIII Congrés Català de Ciències de Laboratori Clínic, Reus, Mar 2018

Ibaretxe. “Impacte clínic del test avançat de lipoproteïnes Liposcale”.  XIII Congrés Català de Ciències de Laboratori Clínic, Reus, Mar 2018

Amigó, N et al. Advanced lipoprotein parameters uncover a hidden atherogenic profile in non-diabetic chronic kidney disease patients. 41 European Lipoprotein Club, Tutzing 2018 (poster presentation).

Gil-Serret, M et al. Exploring lipoprotein patterns in general population with advanced 1H-NMR testing by using an unsupervised clustering approach 41 European Lipoprotein Club, Tutzing 2018 (poster presentation).

Samino, S. et al. Exploring serum metabolomics by advanced 1H-NMR profiling in breast cancer patients. 41 European Lipoprotein Club, Tutzing 2018 (poster presentation).

Gil-Serret, M. et al. Exploring lipoprotein patterns in general population with advanced 1H-NMR testing by using an unsupervised clustering approach 86th EAS Congress, Lisobon, Portugal 2018 (Science at a glance, short communication)

Fuertes, R. et al. Characterization of glycoprotein profiles of type 1 or type 2 diabetes mellitus and atherogenic dyslipidaemia patients by 1H-Nuclear Magnetic Resonance. 86th EAS Congress, Lisobon, Portugal 2018 (poster presentation)

Gil-Serret, M. et al. Advanced NMR lipoprotein analysis in clinical practice. Moving from management of dyslipidaemia to management of lipoprotein patterns. 40 European Lipoprotein Club, Tutzing 2017 (poster presentation).

R. Yahyaoui, E. Rodríguez, M. Gil, MC. García-Jiménez, ML. González-Diéguez, P. Del Valle Loarte, MA Barba-Romero, J. Quintero, D. Gil-Ortega, J. De Las Heras, L. Aldámiz, R. Bernal, E. García and N. Amigó. Characterization of plasma lipoprotein particles in Spanish patients with lysosomal acid lipase deficiency (LAL-D). (AECOM, Las Palmas, 2017, oral presentation; ICIEM, Rio de Janeiro, 2018, poster presentation).

N. Amigó. “Nueva era en el diagnóstico y valoración del riesgo cardiovascular: Análisis de lipoproteínas mediante RMN”. 9th SEMERGEN National Cardiovascular Meetings. Girona 2017.

N. Amigó. “La evaluación de patrones de lipoproteínas y su impacto en el manejo de las dislipemias”. 30th Congress of the Spanish Arteriosclerosis Society, Cádiz 2017.

M. Gil-Serret. “La evaluación de patrones de lipoproteínas y su impacto en el manejo de las dislipemias”. 30thCongress of the Spanish Arteriosclerosis Society, Cádiz 2017.

M. Gil-Serret, D. Ibarretxe, D. Rodriguez, N. Plana, L. Masana and N. Amigó. Análisis avanzado de lipoproteínas por RMN en la práctica clínica. Del manejo de la dislipemia al de patrones lipoproteicos. 30th Congress of the Spanish Arteriosclerosis Society, Cádiz 2017. (Oral presentation).

R. Fuertes, N. Amigó, JC. Vallvé, S. Paredes, D. Taverner, L. Masana and X. Correig. Caracterización del perfil inflamatorio en pacientes con artritis reumatoide frente a población sana mediante 1H-Resonancia Magnética nuclear (1H-NMR). XXX Congreso Nacional de la SEA (Cádiz, 2017. Oral Presentation).

C. Rodríguez-Borjabad, D. Ibarretxe, J. Girona, A. Feliu, N. Amigó, L. Masana, N. Plana. Perfil lipoproteico evaluado por RMN 2D-1H en niños con hipercolesterolemia familiar y no familiar. (Cadiz 2017. Oral presentation).

M. Gil-Serret, E. Correig, D. Ibarretxe, D.  Rodriguez, MA. Pardo, C. Rodriguez, N. Plana, L. Masana & N. Amigó. Advanced NMR lipoprotein analysis in clinical practice. Moving from management of dyslipidaemia to management of lipoprotein patterns. 40 European Lipoprotein Club (Tutzing 2017).

M. Gil-Serret, D. Ibarretxe, N. Plana, L. Masana, X. Correig and N. Amigó. Normal lipoprotein particle number and size in Spanish population according to sex and age, assessed by Nuclear Magnetic Resonance. 85th Congress of the European Atherosclerosis Society, Prague 2017. (Science at a Glance presentation).

R. Fuertes, N. Amigó, JC. Vallvé, S. Paredes, D. Taverner, L. Masana and X. Correig. Characterization of glycoprotein and lipoprotein profile of Rheumatoid arthritis patients by 1H-Nuclear Magnetic Resonance Spectroscopy (1H-NMR). 84th European Atherosclerosis Society (EAS) Congress. (Prague, 2017. Poster Presentation).

C. Malagelada, et al. Metabolic signature of the postprandial experience. United European Gastroenterology (Barcelona, 2017. Poster Presentation).

J. Miranda, RV. Simoes, C. Paules, N. Amigó, M. Pardo, ML. García-Martín, F. Figueras, E. Eixarch, F. Crispi and E. Gratacós. Targeted Lipidomics of Maternal and Cord Blood in Term Gestations with Suboptimal Fetal Growth. 9th International Symposium on Diabetes, Hypertension, Metabolic Syndrome, and Pregnancy (Barcelona, 2017. Poster presentation). **This poster presentation was awarded as best abstract award

R. García, E. Garcés, A. Català, D. Ibarreche, N. Amigó, M. Heras, S. Parra & A. Castro. Factores asociados a la progresión de la arteriosclerosis subclínica en pacientes con lupus eritematoso sistémico. XXXVIII Congreso de la SEMI (Madrid 2017)

R. Fuertes. Caracterización del perfil de glicoproteínas en pacientes con Artritis Reumatoide (AR) frente a población sana mediante ressonància magnètica nuclear de protón (1H –RMN). II Seminari IISPV, 6 Julio 2017.

 N. Amigó. “Importancia del tamaño de las lipoproteínas en el cribado del riesgo cardiovascular: LIPOSCALE”. 8th SEMERGEN National Cardiovascular Meetings, Santander 2016.

N. Amigó. “Importancia del tamaño de las lipoproteínas en el cribado cardiovascular: de la teoría a la práctica clínica”. 29th Congress of the Spanish Arteriosclerosis Society, Granada 2016.

N. Amigó “La Metabolómica por RMN en el Entorno Clínico. Aplicaciones en la Investigación Biomédica y el Diagnóstico Clínico”. Valencia 2016.

M. Gil-Serret. “LIPOSCALE: Caracterización avanzada de lipoproteínas por espectroscopia de resonancia magnética nuclear (1H-RMN). De la investigación a la práctica clínica”. 26thSANAC Autumn Meeting of the Clinical Analysis Andalusian Society, Ronda 2016.

N. Amigó, R. Fuertes, C. Cabré, M. Vinaixa, M. Romeu, M. Muñoz, M. Giralt, J. Soler, J. Aguilera, MT. Compte, X. Correig and A. Martínez-Vea. Pro atherogenic lipoprotein profile associated with white matter lesions in chronic kidney disease patients: A 1H-NMR metabolomic approach. Innsbruck, EAS 2016 (Science at a Glance presentation). **This poster was awarded as best poster award

J. Girona, D. Ibarretxe, N. Plana, S. Guaita-Esteruelas, N. Amigo, M. Heras and L. Masana, PCSK9 Circulating levels and CETP Plasma activity are associated independently of lipid lowering therapies. Innsbruck, EAS 2016 (Science at a Glance presentation). **This poster was awarded as best poster award

N. Amigó, R. Fuertes, C. Cabré, M. Vinaixa, M. Romeu, M. Muñoz, M. Giralt, J. Soler, J. Aguilera, MT. Compte, X. Correig, A. Martínez-Vea. Metabolomic approach to white matter lesions in chronic haemodialysis patients identifies a novel metabolic profile associated with these lesions. Viena, ERA-EDTA 2016 (Poster presentation).

N. Amigó, R. Fuertes, C. Cabré, M. Vinaixa, M. Romeu, M. Muñoz, M. Giralt, J. Soler, J. Aguilera, MT. Compte, X. Correig, A. Martínez-Vea. Aproximación metabolómica con 1H-RMN para la caracterización de pacientes con enfermedad renal crónica en hemodiálisis que presentan lesiones en la sustancia blanca cerebral. Oviedo, SEN 2016 (Poster presentation).

R. Fuertes, N. Amigó, JC. Vallvé, S. Paredes, D. Taverner, L. Masana and X. Correig. Caracterización metabolómica de pacientes con artritis reumatoide a través de 1H-Resonancia Magnética nuclear (1H-NMR). XXIX Congreso Nacional de la SEA , Granada 2016.

R. Fuertes “BIOSFER TESLAB SL, from Research to Clinical Practice. Characterization of Rheumatoid Arthritis (RA) patients by 1H-Nuclear Magnetic Resonance Spectroscopy (1H-NMR)”. Retreat Científic Institut d’investigació Sanitària Pere Virgili (IISPV), Tortosa 16 – 17 Noviembre 2016.

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 N. Amigó, A. O. Akinkuoli, S. E. Chiuve, N. R. Cook. S. Mora. Fish Consumption, Omega-3 fatty acids (N-3) and NMR Lipoprotein Subfractions in 26034 apparently healthy women. (NLF Reykjavik 2015, Oral Presentation; ISA Amsterdam 2015, Oral Presentation; SEA Logroño 2015, Oral Presentation).**This presentation was awarded as original research

R. Mallol, N. Amigó, M. A. Rodríguez, M. Heras, M. Vinaixa, N. Plana, E. Rock, J. Ribalta, O. Yanes, L. Masana and X. Correig. Discordance analysis between LDL particle concentrations and LDL-C and ApoB values in type 2 diabetic subjects with atherogenic dyslipidemia. (ISA 2015 Amsterdam, Oral Presentation).

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R. Yahyaoui, E. Rodríguez-García, M. Heras, MC García-Jiménez, ML González-Diéguez, R. Mallol and N. Amigó. Characterization of plasma lipoprotein particles in Spanish patients with lysosomal acid lipase deficiency (SSIEM Lyon 2015, Poster Presentation).

MC. García-Jiménez, P. Roncalés, L. Monge, I. Ros, J. Cebolla, E Rodríguez-García, N. Amigó, M. Heras and R. Yahyaoui. Deficiencia de lipasa ácida lisosomal: una causa poco reconocida de dislipemia y disfunción hepática. (ECM Pamplona 2015, Poster Presentation).

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N. Amigó, R. Mallol, M. Heras, A. Cabré, N.Plana, L.Masana and X. Correig. Smaller and ‘herniated’ high density lipoproteins incremented in type 2 diabetes mellitus patients (SED Valencia 2015, Oral Presentation).

CB. Dias, N. Amigó, LG. Wood and ML. Garg. Saturated fats and vegetable oil modulate lipoprotein profile similarly when co-administered with omega-3 polyunsaturated fatty acids (FSDH Wellington 2015, Oral Presentation).

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S. Parra, N. Canela, M. Heras, N. Amigó, P. Sahun, X. Correig and A. Castro Proteome analyses of HDL particles allows to identify biomarkers of disease activity in SLE patients: Gelsolin, Indian Hedgehog protein and S100A8 (EULAR Rome 2015, Poster Presentation).

R. Mallol, A Cabré, N. Amigó, M. Heras, L. Masana, X. Correig. Characterisation of Atherogenic Dyslipidaemia using a novel NMR-based advanced lipoprotein test in type 2 diabetic subjects. XVII Congreso Nacional de la Sociedad Española de Arteriosclerosis, Barcelona (Spain) February 20-21. 2014. **This poster won the 3rd award for the best communication at the Conference

N. Amigó, R. Mallol, M. Heras, A Cabré, N. Plana, L. Masana, X. Correig. Smaller and “Herniated” HDL in patients with type 2 diabetes mellitus. XVII Congreso Nacional de la Sociedad Española de Arteriosclerosis, Barcelona (Spain) February 20-21. 2014.

R. Mallol, A Cabré, M. Rodríguez, N. Amigó, M. Vinaixa, N. Plana, M. Heras, L. Masana, X. Correig. Characterisation of Atherogenic Dyslipidemia using a novel NMR-based advanced lipoprotein test in type 2 diabetic subjects. 81st European Atherosclerosis Society Congress, Lyon (France) June 2-5. 2013.

R. Mallol, N. Amigó, M. Rodríguez, M. Heras, N. Plana, L. Masana, X. Correig. Advanced Lipoprotein Testing Using Diffusion-edited 1H NMR Spectroscopy. 25 Congreso Nacional de la Sociedad Española de Arteriosclerosis, Reus (Spain) June 6-8. 2012.