Mejora en la predicción de enfermedad cardiovascular ateromatosa mediante el test Liposcale
Los pacientes con enfermedad renal crónica (ERC) presentan una elevada carga de enfermedad cardiovascular ateromatosa que no se explica totalmente por los parámetros lipídicos tradicionales. Un estudio publicado en la revista clinical Kidney journal, realizado en pacientes con enfermedad renal crónica, revela que la información sobre la composición de las lipoproteínas i el número de […]
Particle size measurement of lipoprotein fractions using diffusion-ordered NMR spectroscopy
Abstract The sizes of certain types of lipoprotein particles have been associated with an increased risk of cardiovascular disease. However, there is currently no gold standard technique for the determination of this parameter. Here, we propose an analytical procedure to measure lipoprotein particles sizes using diffusion-ordered nuclear magnetic resonance spectroscopy (DOSY). The method was tested […]
Surface fitting of 2D diffusion-edited 1H NMR spectroscopy data for the characterisation of human plasma lipoproteins
Abstract Determining the concentration and size of lipoprotein complexes is very important due to their role in cardiovascular diseases and metabolic disorders. However, standard methods for lipoprotein fractionation are manual and time consuming and cannot be used as standard diagnostic tools. Because different subclasses of lipoproteins have different radii and, hence, different diffusion velocities, we […]
